August 1, 2005European Journal of Cardiovascular Prevention & RehabilitationOpen Access

Running exercise of different duration and intensity: effect on endothelial progenitor cells in healthy subjects

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Why the study?

Does running exercise of different duration and intensity increase circulating endothelial progenitor cell numbers in healthy subjects?

Structured PICO

Does running exercise of different duration and intensity increase circulating endothelial progenitor cell numbers in healthy subjects?

Population

25 healthy volunteers

Intervention

Three protocols of running exercise: intensive running (30 min at 100% of the velocity of the individual anaerobic threshold [IAT]), moderate running (30 min at 80% of the velocity of the IAT), and moderate short-term running (10 min)

Comparator

Control levels

Outcome

Circulating endothelial progenitor cell (EPC) numbers quantified by flow cytometry and cell culturesurrogate

Moderate and intensive running for 30 minutes significantly increases circulating endothelial progenitor cells in healthy subjects, providing a potential cellular mechanism for the cardiovascular benefits of exercise.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support exercise as modulator of vascular repair; extends observational EPC data but leaves clinical translation open pending trials.

Cite This Study

Laufs et al. (2005) studied this question.

synapsesocial.com/papers/6a7d246fd3686d25b46e4c57 https://doi.org/10.1097/01.hjr.0000174823.87269.2e

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Running exercise of different duration and intensity: effect on endothelial progenitor cells in healthy subjects

Structured PICO

Discussion

Implication

Cite This Study

Running exercise of different duration and intensity: effect on endothelial progenitor cells in healthy subjects

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider