November 19, 2021Frontiers in PhysiologyOpen Access

Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases

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Why the study?

To understand TMEM16 proteins in health and disease, it is critical to decipher their molecular mechanisms of activation gating and regulation.

Population

TMEM16 proteins

Design

Review

Authors

SLSon C. LeDuke University PLPengfei LiangCentral South University ALAugustus J. LowryDuke University

Discussion

Member takes

Implication

TMEM16 proteins link to multiple diseases; leaves open gating mechanisms before therapeutic targeting.

Structured PICO

Population

TMEM16 proteins (ion channels and scramblases)

Provides a comprehensive overview of the structural features, gating, and regulatory mechanisms of TMEM16 proteins, which are implicated in various human diseases.

Cite This Study

Le et al. (2021) studied this question.

synapsesocial.com/papers/6a72d4b79da973292f087201 https://doi.org/10.3389/fphys.2021.787773

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Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider