Answers are grounded in this paper and cite their sources.
Endotoxin is taken up by macrophages by pinocytosis. Various properties (i.e., the ability to induce the Shwartzman phenomenon and the immunogenicity of endotoxin taken up by macrophages) are not altered for 48 hr. Endotoxin taken up by macrophages is transferred to autologous lymphocytes that adhere to macrophages, forming lymphocyte-macrophage islets.
No takes yet. Share an insight, caveat, or question.
Constantin A. Bona (1973) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: