Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
January 1, 2007Circulation JournalOpen Access

Atherosclerotic Plaque Characterization by 0.5-mm-Slice Multislice Computed Tomographic Imaging Comparison With Intravascular Ultrasound

View Full Paper
Ask AI
Bookmark
Share

Authors

SMSadako MotoyamaTKTakeshi KondoHAHirofumi Anno

Discussion

Loading...

Member takes

Overview

Comparative study demonstrates accurate differentiation of coronary plaque types by multislice computed tomography against intravascular ultrasound, highlighting reliable noninvasive imaging.

Key Points

  • To evaluate whether 0.5-mm-slice multislice computed tomography (MSCT) can accurately differentiate coronary atherosclerotic plaque composition compared with invasive intravascular ultrasound (IVUS).
  • Analyzed 98 coronary plaques classified by IVUS echogenicity as soft (n=18), fibrous (n=40), or calcified (n=40) in 37 consecutive patients undergoing percutaneous interventions.
  • Calculated 0.5-mm-slice MSCT density in Hounsfield units (HU) across 443 regions of interest, including 331 lesional foci and 112 luminal cross-sections, using the Kruskal-Wallis test.
  • MSCT density differed significantly among plaque subtypes: 11±12 HU for soft plaques, 78±21 HU for fibrous plaques, and 516±198 HU for calcified plaques (p<0.0001).
  • Contrast-filled luminal density averaged 258±43 HU, showing statistically significant separation from soft, fibrous, and calcified plaque tissues (p<0.0001).

Cite This Study

Motoyama et al. (2007) studied this question.

synapsesocial.com/papers/6a72dc44439a8a41ba1ae5ffhttps://doi.org/10.1253/circj.71.363
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Coronary Arterial Plaque Characterized by Multislice Computed Tomography Predicts Coronary Events Following Coronary Intervention2006
  2. 2Plaque Characterization of Atherosclerotic Coronary Arteries by Intravascular Ultrasound1990 · 51 citations
  3. 3Plaque Quantification by Coronary CT and Intravascular Ultrasound Identifies a Low CT Density Core as a Marker of Plaque Instability in Acute Coronary Syndromes2014 · 42 citations
  4. 4Carotid Plaque Characterization with Contrast-Enhanced Ultrasound Imaging and its Histological Validation2010 · 11 citations
  5. 5An Objective Characterization of Atherosclerotic Lesion2000 · 36 citations