Why the study?
Do specific genetic polymorphisms of the renin-angiotensin-aldosterone system increase the risk of arterial hypertension in the Italian population?
Do specific genetic polymorphisms of the renin-angiotensin-aldosterone system increase the risk of arterial hypertension in the Italian population?
Certain allelic variants of RAAS genes (AGT, AT1, ALDO) carry a small but identifiable risk of developing arterial hypertension in the Italian population.
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These RAAS alleles were associated with hypertension in Italians; hypothesis-generating, should not yet change practice.
Castellano et al. (2003) studied this question.
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