Population
1021 consecutive patients with heart failure with reduced ejection fraction under guideline-directed medical…
Design
Cohort
Follow-up
5 years
Authors
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Moderate/severe BVFR may refine mortality risk stratification in HFrEF; leaves open whether targeted valvular interventions improve outcomes.
Bivalvular functional regurgitation is a common entity in HFrEF, and its presence and severity are independently associated with adverse cardiac remodeling and increased long-term mortality.
Bartko et al. (2018) studied this question.
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