Why the study?
Does smoking habit affect aortic pulse wave velocity in male adults with arteriosclerotic diseases?
Does smoking habit affect aortic pulse wave velocity in male adults with arteriosclerotic diseases?
Smoking is associated with increased aortic pulse wave velocity, an index of arteriosclerosis, in adult males with arteriosclerotic diseases.
Smoking may worsen arterial stiffness by age in vascular disease; hypothesis-generating, requires longitudinal data before practice implications.
We measured aortic pulse wave velocity (PWV) in 168 male adult cases of various arteriosclerotic diseases. In order to evaluate the effects of age, smoking habits, alcohol intake, and blood pressure, we applied the least median of squares (LMS) regression which was considered to be very useful for data analysis. The results showed that PWV level increased with age. Furthermore smoking was associated with increasing PWV level and this effect was also related to age. We concluded that the PWV was valuable as an index of arteriosclerosis, and instead of the classical least squares method, LMS regression was very useful for analysis of medical data.
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Nakamoto et al. (1989) studied this question.
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