Population
14 patients with a discovered 'lupus' anticoagulant
Design
Case_series
Authors
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May link lupus anticoagulant to thrombosis via prostacyclin inhibition even without SLE; hypothesis-generating and requires validation before clinical adoption.
Inhibition of prostacyclin formation by lupus anticoagulant may play a major role in the pathogenesis of thrombosis and obstetrical complications, even without systemic lupus erythematosus.
Carreras et al. (1982) studied this question.
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