Key result
Treatment with steroids and antiaggregants in patients with lupus anticoagulant and prior fetal death resulted in 13 live births out of 27 pregnancies (48.1%).
Why the study?
Does treatment with prednisone and antiaggregants improve live birth rates in pregnant patients with lupus anticoagulant?
Population
19 pregnant patients with lupus anticoagulant and a history of fetal death or related complications
Design
Case_series
Authors
Loading...
May support steroids plus antiaggregants after prior fetal loss; hypothesis-generating and should not change practice without RCTs.
Observational (n=19)
Does treatment with prednisone and antiaggregants improve live birth rates in pregnant patients with lupus anticoagulant?
Treatment with steroids and antiaggregants may be beneficial for second and third-trimester fetal death and clinical SLE, but its role in primary habitual abortion or patients without previous fetal loss is questionable.
Carp et al. (2010) conducted an observational in Fetal demise associated with lupus anticoagulant (n=19). Prednisone and antiaggregants was evaluated on Live births. Treatment with steroids and antiaggregants in patients with lupus anticoagulant and prior fetal death resulted in 13 live births out of 27 pregnancies (48.1%).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: