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November 1, 1975Circulation ResearchOpen Access

Potassium influx in the frog atrium during the cardiac cycle.

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Population

Frog atrial trabeculae

Design

Preclinical

Authors

DJDAVID F. JUNCKERPLP Y LeeEGE. Anne GreeneHuntington Hospital

Discussion

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Implication

Animal data on 42K influx should not guide therapy; leaves open Na+, K+-ATPase contributions in human cardiac cycles.

Structured PICO

P
Population
Frog atrial trabeculae
I
Intervention
Exposure to radioactive 42K pulses at selected points in the cardiac cycle
O
Outcome
42K influx profile during the cardiac cyclesurrogate

Demonstrated a characteristic 42K influx profile in frog atrial fibers during the cardiac cycle, reflecting membrane Na+, K+-ATPase activity.

Cite This Study

JUNCKER et al. (1975) studied this question.

synapsesocial.com/papers/6a72e0448468324a26748582https://doi.org/10.1161/01.res.37.5.597
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