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February 27, 2008Neuropsychobiology

Smoking panic disorder patients had significantly higher supine HR, standing diastolic BP, standing mean BP, and cardiac load compared to nonsmoking patients and controls, while lipid values in panic disorder patients showed no significant risk compared to reference values.

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Why the study?

Does smoking increase cardiovascular risk factors (HR, BP) in patients with panic disorder compared to nonsmokers and healthy controls?

Population

19 nonsmoking normal controls, 29 smoking patients with panic disorder, and 36 nonsmoking patients with…

Comparison

Smoking (in patients with panic disorder) vs Nonsmoking panic disorder patients and…

Design

Cross-sectional

Authors

VYVikram K. YeraganiRPR. O. PohlRBRichard Balon

Discussion

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Overview

Smoking may drive higher HR and BP in panic disorder; hypothesis-generating and should not yet change practice.

Structured PICO

Does smoking increase cardiovascular risk factors (HR, BP) in patients with panic disorder compared to nonsmokers and healthy controls?

P
Population
19 nonsmoking normal controls, 29 smoking patients with panic disorder, and 36 nonsmoking patients with panic disorder (for HR/BP measures); 92 panic disorder patients for lipid analysis.
I
Intervention
Smoking (in patients with panic disorder)
C
Comparator
Nonsmoking panic disorder patients and nonsmoking normal controls
O
Outcome
Supine and standing heart rate (HR), blood pressure measures, and lipid values (total cholesterol, HDL, LDL)surrogate

Smoking, rather than panic disorder itself, appears to be the primary driver of increased heart rate and blood pressure in patients with panic disorder, while lipid profiles remain unaffected.

Cite This Study

Yeragani et al. (2008) studied this question.

synapsesocial.com/papers/6a72e0afda24de05641ae69ahttps://doi.org/10.1159/000119440
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1EVALUATION OF HEART RATE VARIABILITY IN DRUG FREE PANIC DISORDER PATIENTS2018 · 1 citations
  2. 2Heart rate and blood pressure changes during postural change and isometric handgrip exercise in patients with panic disorder and normal controls1990 · 36 citations
  3. 3Evaluation of Heart Rate Variability in Drug Free Panic Disorder Patients2017 · 3 citations
  4. 4The differences between patients with panic disorder and healthy controls in psychophysiological stress profile2018 · 19 citations
  5. 5Ambulatory Blood Pressure Monitoring in Patients With Panic Disorder1987 · 31 citations