Why the study?
Does high-intensity exercise improve insulin- and IGF-1-mediated vasorelaxation in spontaneously hypertensive rats?
Population
Sixteen-week-old spontaneously hypertensive rats (SHR) and age-matched Wistar-Kyoto rats (WKY)
Comparison
High-intensity exercise vs Non-exercise sedentary SHR and normotensive WKY…
Design
Preclinical, randomly divided
Follow-up
Immediately after exercise
Authors
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Should not change hypertension management; hypothesis-generating for exercise effects on vascular insulin sensitivity, needing human trials.
Does high-intensity exercise improve insulin- and IGF-1-mediated vasorelaxation in spontaneously hypertensive rats?
High-intensity exercise enhances insulin- and IGF-1-mediated vasorelaxation in hypertensive rats via an endothelium-dependent pathway involving reduced superoxide production.
Ai‐Lun Yang (2011) studied this question.
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