Why the study?
Does voluntary running at different intensity levels improve blood pressure, endothelium-dependent vessel dysfunction, and insulin resistance in aged spontaneously hypertensive rats?
Population
Ten-month-old male and female spontaneously hypertensive rats (SHR) with severe hypertension
Comparison
Voluntary running at either low intensity or… vs Age-matched Wistar-Kyoto rats and SHR kept under…
Design
Preclinical
Follow-up
6 weeks
Authors
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Low-intensity exercise shows promise in aged SHR models; hypothesis-generating for human hypertension, should not change practice.
Does voluntary running at different intensity levels improve blood pressure, endothelium-dependent vessel dysfunction, and insulin resistance in aged spontaneously hypertensive rats?
Low-intensity voluntary exercise lowers blood pressure and improves endothelium-dependent vessel relaxation and insulin sensitivity in aged spontaneously hypertensive rats.
Sun et al. (2008) studied this question.
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