Why the study?
Does voluntary exercise lower resting blood pressure in young spontaneously hypertensive and stroke-prone hypertensive rats?
Population
Young spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats, aged 28-35 days at…
Comparison
Voluntary exercise in activity cages for 12 weeks. vs Sedentary cages (no voluntary exercise).
Design
Preclinical
Follow-up
12 weeks
Authors
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May lower BP in SHR but not SP-SHR; leaves open human translation and mechanisms.
Does voluntary exercise lower resting blood pressure in young spontaneously hypertensive and stroke-prone hypertensive rats?
Voluntary exercise lowers resting blood pressure and improves fitness in young spontaneously hypertensive rats, but does not confer the same blood pressure or survival benefits in stroke-prone hypertensive rats.
Overton et al. (1986) studied this question.
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