Narrative review evaluates cannabidiol's anti-biofilm effects in dysbiosis-related oral conditions, suggesting new oral health applications.
Key Points
This review aims to evaluate the therapeutic potential of cannabidiol in managing dysbiosis-related oral biofilm diseases such as dental caries and periodontal diseases.
Conducted a narrative review of literature on cannabidiol's effects on oral biofilms, focusing on antibiofilm and antivirulence evidence.
Analyzed current findings from preclinical and model-dependent studies regarding cannabidiol's impact on oral health.
Discussed limitations such as hydrophobicity and stability issues affecting cannabidiol's translation into clinical practice.
Cannabidiol inhibits biofilm formation and reduces cariogenic and fungal virulence traits.
Modulates host inflammatory responses and promotes tissue-protective reactions in oral health contexts.
Identifies barriers to clinical application, including uncertain dosing and delivery challenges.