Why the study?
Does PCI with everolimus eluting stents compared to CABG improve mid-term adverse cardiovascular outcomes in patients with coronary artery disease?
Population
5,207 patients with coronary artery disease from 4 studies (2 RCTs, 2 observational studies).
Comparison
Percutaneous Coronary Intervention with… vs Coronary Artery Bypass Surgery (CABG)
Design
Meta-analysis
Follow-up
mid-term (>1 year but less than 5 years)
Authors
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CABG lowers mid-term MACE and MI versus EES-PCI with similar mortality; extends prior comparisons yet mixed designs leave strategy choice open.
Does PCI with everolimus eluting stents compared to CABG improve mid-term adverse cardiovascular outcomes in patients with coronary artery disease?
In patients with coronary artery disease, PCI with everolimus-eluting stents yields similar mid-term mortality to CABG, but is associated with higher rates of myocardial infarction, MACE, and repeat revascularization.
Bundhun et al. (2016) studied this question.