Population
38 subjects undergoing cardiopulmonary bypass, age 32 to 85 (median 69 years)
Design
Cohort
Authors
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Heterogeneous fibrinolytic responses to CPB associate with ischemic time; leaves open whether PAI-1 patterns guide individualized perioperative strategies.
The fibrinolytic response to cardiopulmonary bypass is highly heterogeneous among individuals, with distinct patterns influenced by surgery type and ischemic time.
Chandler et al. (1995) studied this question.
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