Why the study?
Do elevated PAI-1 concentrations predict the development of postoperative atrial fibrillation in adult patients undergoing elective cardiac surgery requiring cardiopulmonary bypass?
Population
253 adult patients undergoing elective cardiac surgery requiring cardiopulmonary bypass who were in sinus…
Design
Cohort
Authors
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Elevated PAI-1 may refine postoperative AF risk assessment after cardiac surgery; hypothesis-generating and should not yet change practice.
Do elevated PAI-1 concentrations predict the development of postoperative atrial fibrillation in adult patients undergoing elective cardiac surgery requiring cardiopulmonary bypass?
Elevated preoperative or postoperative PAI-1 antigen concentrations independently predict the development of atrial fibrillation after cardiopulmonary bypass.
Pretorius et al. (2007) studied this question.
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