Why the study?
Are elevated levels of Plasminogen activator inhibitor-1 (PAI-1) associated with the development of postoperative atrial fibrillation after cardiopulmonary bypass?
Population
100 patients undergoing cardiac surgery requiring cardiopulmonary bypass who were in sinus rhythm at the…
Design
Cohort
Authors
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Elevated PAI-1 may aid POAF risk stratification after CPB; hypothesis-generating and requires prospective validation before clinical adoption.
Are elevated levels of Plasminogen activator inhibitor-1 (PAI-1) associated with the development of postoperative atrial fibrillation after cardiopulmonary bypass?
Elevated preoperative and post-CPB levels of PAI-1 may serve as useful predictors for the development of postoperative atrial fibrillation in patients undergoing cardiac surgery.
Fawzy et al. (2018) studied this question.
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