Key result
The presence of metabolic syndrome in obese individuals did not significantly worsen myocardial performance index (0.58 vs 0.57, p=0.694) or diastolic function compared to obesity alone.
Why the study?
This study was conducted to investigate the effect of the presence or absence of metabolic syndrome on cardiac structure and function in obese individuals.
Does the presence of metabolic syndrome worsen diastolic function and myocardial performance index in obese individuals?
Cross-Sectional (n=125)
No
Does the presence of metabolic syndrome worsen diastolic function and myocardial performance index in obese individuals?
Obesity may independently contribute to subclinical myocardial dysfunction, as the addition of metabolic syndrome did not significantly worsen echocardiographic parameters of diastolic function or myocardial performance in obese patients.
Obesity may predominate in impairing myocardial function; leaves open metabolic syndrome's independent contribution.
Aim: This study investigated the effect of the presence or absence of metabolic syndrome (MetS) on cardiac structure and function in obese individuals.Materials and Methods: A retrospective, cross-sectional, and observational study design was used.125 patients diagnosed with obesity were included in the study and divided into two groups according to the presence of MetS.Demographic, clinical, and echocardiographic data of the patients were analyzed.Results: No significant difference was found in diastolic functions and myocardial performance index (MPI) between obese individuals with and without MetS.However, a trend was observed in these parameters compared to the normal population in both groups.Systolic blood pressure, triglyceride, LDL-cholesterol, and total cholesterol levels were significantly higher in the MetS group than in the non-MetS group.Discussion: Obesity may have adverse effects on cardiac structure and function, regardless of the presence of MetS.Therefore, echocardiography is an important tool for the assessment and management of cardiovascular risks in obese individuals, even if they do not develop MetS.Targeted strategies such as lifestyle changes, pharmacological treatments, and regular cardiac monitoring should be developed to protect and improve the cardiovascular health of patients with obesity and MetS.
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Özmen et al. (2025) conducted a cross-sectional in Obesity (n=125). Metabolic syndrome vs. Obese patients without metabolic syndrome was evaluated on Myocardial performance index (MPI) (p=0.694). The presence of metabolic syndrome in obese individuals did not significantly worsen myocardial performance index (0.58 vs 0.57, p=0.694) or diastolic function compared to obesity alone.
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