Key result
Higher BMI and central adiposity significantly predicted worse cardiac autonomic function, including lower SDNN and RMSSD (P < .05), in youth with type 1 diabetes followed over 7 years.
Why the study?
Does higher BMI and adiposity predict worse cardiac autonomic function in patients with childhood-onset type 1 diabetes?
Population
253 participants with childhood-onset type 1 diabetes (aged 8-30 years), assessed at a tertiary hospital.
Design
Cohort
Follow-up
over 7 years
Authors
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Adiposity may worsen autonomic function in youth with T1D; hypothesis-generating and should not yet change practice.
Cohort (n=253)
No
Does higher BMI and adiposity predict worse cardiac autonomic function in patients with childhood-onset type 1 diabetes?
p-value: p=< .05
Higher BMI and central adiposity independently predict the development of cardiac autonomic dysfunction in adolescents and young adults with type 1 diabetes.
Cho et al. (2018) conducted a cohort in Type 1 diabetes (n=253). Higher body mass index and adiposity was evaluated on Heart rate variability measures (SDNN, RMSSD, TI, LF:HF) (p=< .05). Higher BMI and central adiposity significantly predicted worse cardiac autonomic function, including lower SDNN and RMSSD (P < .05), in youth with type 1 diabetes followed over 7 years.
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