Key result
Among 61 domestic dogs with parvovirus-like symptoms in China, 55.7% tested positive for CPV-2, with the CPV-2c variant increasing in prevalence and replacing CPV-2a as the dominant strain.
Why the study?
CPV-2 exhibits high substitution rates close to RNA viruses, making the tracing of its prevalence in dogs clinically significant.
Population
61 samples from domestic dogs in Guangdong Province, China, and Chinese VP2 isolates from the NCBI database
Design
Aetiological survey and database sequence analysis
Authors
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CPV-2c emergence in Chinese dogs supports enhanced variant surveillance; leaves open questions on vaccine efficacy against shifting strains.
Cross-Sectional (n=61)
Yes
The study highlights that CPV-2c is rapidly becoming the dominant variant of canine parvovirus in China, which may have implications for vaccine efficacy.
Hao et al. (2020) conducted a cross-sectional in Canine parvovirus infection (n=61). CPV-2c variant vs. Other CPV-2 variants was evaluated on CPV-2 positivity by PCR detection and virus isolation. Among 61 domestic dogs with parvovirus-like symptoms in China, 55.7% tested positive for CPV-2, with the CPV-2c variant increasing in prevalence and replacing CPV-2a as the dominant strain.
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