Key result
Elevated cardiorespiratory fitness in endurance athletes was associated with a delayed onset of cerebral autoregulation after sit-to-stand (3.1 vs 1.5 seconds, p=0.03) compared to controls.
Why the study?
Does elevated cardiorespiratory fitness alter dynamic cerebral autoregulatory capacity during changes in mean arterial pressure in healthy males?
Population
27 healthy males, comprising 19 endurance-trained athletes and 8 inactive/moderately active controls.
Comparison
Elevated cardiorespiratory fitness vs Inactive/moderately active lifestyle (controls)
Design
Cross-sectional
Authors
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Suggests potential orthostatic vulnerability in athletes; leaves open clinical relevance and need for prospective studies.
Cross-Sectional (n=27)
No
Does elevated cardiorespiratory fitness alter dynamic cerebral autoregulatory capacity during changes in mean arterial pressure in healthy males?
Absolute Event Rate: 3.1% vs 1.5%
p-value: p=0.03
Elevated cardiorespiratory fitness is associated with an attenuated capability of the cerebral vasculature to counter rapid and large changes in mean arterial pressure, despite an intact response to spontaneous oscillations.
Labrecque et al. (2017) conducted a cross-sectional in Healthy (elevated cardiorespiratory fitness) (n=27). Elevated cardiorespiratory fitness (Endurance training) vs. Inactive/moderately active controls was evaluated on Time delay before onset of regulation after sit-to-stand (seconds) (p=0.03). Elevated cardiorespiratory fitness in endurance athletes was associated with a delayed onset of cerebral autoregulation after sit-to-stand (3.1 vs 1.5 seconds, p=0.03) compared to controls.
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