Why the study?
Is the ALDH2 *2 allele associated with blood pressure levels and hypertension prevalence in a Japanese population?
Population
2,395 adults living in a mountainous farming region near Kyoto, Japan, free from cardiovascular disease and…
Comparison
ALDH2 *2 allele (genotypes *1/*2 and *2/*2) vs ALDH2 *1/*1 genotype (not having *2 allele)
Design
Cross-sectional
Authors
Loading...
ALDH2 genotyping should not inform hypertension risk assessment; leaves open alcohol-independent effects in other subgroups.
Is the ALDH2 *2 allele associated with blood pressure levels and hypertension prevalence in a Japanese population?
The ALDH2 genotype does not appear to have a direct causal relationship with hypertension independent of alcohol consumption in a Japanese population.
Amamoto et al. (2002) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: