Why the study?
RDW predicts prognosis in CAD patients after PCI, but whether the association between RDW and mortality is linear or non-linear had not been demonstrated.
Does higher red cell distribution width (RDW) predict increased 1-year all-cause and cardiovascular mortality in patients undergoing PCI?
Population
10,669 patients undergoing PCI
Comparison
Five RDW groups with the lowest (<=13.3%) as reference
Design
Multicenter retrospective cohort study
Follow-up
1 year
Key result
Higher red cell distribution width was linearly associated with increased 1-year all-cause mortality in patients undergoing PCI (HR 2.689 for highest vs lowest RDW group; p for trend = 0.006).
Authors
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May refine post-PCI risk stratification in CAD; leaves open linear versus non-linear RDW-mortality associations.
Cohort (n=10,669)
Yes
Does higher red cell distribution width (RDW) predict increased 1-year all-cause and cardiovascular mortality in patients undergoing PCI?
Hazard Ratio: 2.689
p-value: p=0.006
Higher red cell distribution width (RDW) is an independent, linear predictor of 1-year all-cause and cardiovascular mortality in patients undergoing PCI.
Liao et al. (2021) conducted a cohort in Coronary artery disease following percutaneous coronary intervention (n=10,669). Higher red cell distribution width (RDW) vs. Lowest RDW (≤13.3%) was evaluated on 1-year all-cause mortality (HR 2.689, p=0.006). Higher red cell distribution width was linearly associated with increased 1-year all-cause mortality in patients undergoing PCI (HR 2.689 for highest vs lowest RDW group; p for trend = 0.006).
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