Key result
An elevated red blood cell distribution width was associated with higher long-term all-cause mortality compared to RDW <12.8%.
Why the study?
Evidence concerning prognostic biomarkers among patients with cancer undergoing PCI is scarce, despite the rising prevalence of coronary heart disease with cancer.
Does elevated red blood cell distribution width predict long-term all-cause mortality in patients undergoing PCI with a previous history of cancer?
Cohort (n=172)
Does elevated red blood cell distribution width predict long-term all-cause mortality in patients undergoing PCI with a previous history of cancer?
Answers are grounded in this paper and cite their sources.
Elevated red blood cell distribution width (≥13.5%) is a strong independent predictor of long-term all-cause mortality in patients with a history of cancer undergoing PCI.
Background: The number of patients suffering from coronary heart disease with cancer is rising. There is scarce evidence concerning the biomarkers related to prognosis among patients undergoing percutaneous coronary intervention (PCI) with cancer. Thus, the aim of this study was to investigate the association between red blood cell distribution width (RDW) and prognosis in this population.Methods: A total of 172 patients undergoing PCI with previous history of cancer were enrolled in this retrospective study. The endpoint was long-term all-cause mortality. According to tertiles of RDW, the patients were classified into three groups: Tertile 1 (RDW <12.8%), Tertile 2 (RDW ≥12.8% and <13.5%) and Tertile 3 (RDW ≥13.5%).Results: During an average follow-up period of 33.3 months, 29 deaths occurred. Compared with Tertile 3, mortality of Tertile 1 and Tertile 2 was significantly lower in the Kaplan–Meier analysis. In multivariate Cox regression analysis, RDW remained an independent risk factor of mortality (HR: 1.938, 95% CI: 1.295–2.655, p < 0.001). The all-cause mortality in Tertile 3 was significantly higher than that in Tertile 1 (HR: 5.766; 95% CI: 1.426–23.310, p = 0.014).Conclusions: An elevated RDW level (≥13.5%) was associated with long-term all-cause mortality among patients undergoing PCI with previous history of cancer.
No takes yet. Share an insight, caveat, or question.
Yang et al. (2020) conducted a cohort in coronary heart disease with cancer (n=172). Elevated red blood cell distribution width (RDW ≥13.5%) vs. RDW <12.8% was evaluated on long-term all-cause mortality (HR 5.766, 95% CI 1.426-23.310, p=0.014). An elevated red blood cell distribution width was associated with higher long-term all-cause mortality compared to RDW <12.8%.
Synapse has enriched 10 related papers. Consider them for comparative context: