Why the study?
Evidence concerning prognostic biomarkers among patients with cancer undergoing PCI is scarce, despite the rising prevalence of coronary heart disease with cancer.
Does elevated red blood cell distribution width predict long-term all-cause mortality in patients undergoing PCI with a previous history of cancer?
Population
172 patients undergoing PCI with a previous history of cancer
Comparison
RDW tertiles: Tertile 1 (<12.8%) vs Tertile 2 (≥12.8% to <13.5%) vs Tertile 3 (≥13.5%)
Design
Retrospective study
Follow-up
Average 33.3 months
Key result
An elevated red blood cell distribution width (≥13.5%) was associated with significantly higher long-term all-cause mortality compared to RDW <12.8% (HR 5.766; 95% CI 1.426-23.310; p=0.014).
Authors
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May aid risk stratification; hypothesis-generating and requires prospective validation before clinical use.
Cohort (n=172)
Does elevated red blood cell distribution width predict long-term all-cause mortality in patients undergoing PCI with a previous history of cancer?
Hazard Ratio: 5.766 (95% CI 1.426–23.31)
p-value: p=0.014
Elevated red blood cell distribution width (≥13.5%) is a strong independent predictor of long-term all-cause mortality in patients with a history of cancer undergoing PCI.
Yang et al. (2020) conducted a cohort in coronary heart disease with cancer (n=172). Elevated red blood cell distribution width (RDW ≥13.5%) vs. RDW <12.8% was evaluated on long-term all-cause mortality (HR 5.766, 95% CI 1.426-23.310, p=0.014). An elevated red blood cell distribution width (≥13.5%) was associated with significantly higher long-term all-cause mortality compared to RDW <12.8% (HR 5.766; 95% CI 1.426-23.310; p=0.014).
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