Key result
Evening dosing of antihypertensive medications did not significantly reduce the risk of nonfatal myocardial infarction, nonfatal stroke, or vascular death compared to morning dosing (HR 0.95).
Why the study?
Does taking usual blood pressure medications in the evening improve cardiovascular outcomes compared to taking the medications in the morning?
Does taking usual blood pressure medications in the evening improve cardiovascular outcomes compared to taking the medications in the morning?
Evening dosing of antihypertensive medications does not improve cardiovascular outcomes compared to morning dosing, indicating patients can take their medications whenever convenient without harm.
Should blood pressure (BP) medications be taken in the morning or in the evening? The TIME study results were presented at the ESC congress 2022 and published not too long after [1]. TIME was a lar...
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Kjeldsen et al. (2022) conducted an editorial in Hypertension (n=21,104). Evening dosing of antihypertensive medications vs. Morning dosing of antihypertensive medications was evaluated on Composite of hospitalisation for nonfatal myocardial infarction, nonfatal stroke, or vascular death (HR 0.95, 95% CI 0.83-1.10, p=0.53). Evening dosing of antihypertensive medications did not significantly reduce the risk of nonfatal myocardial infarction, nonfatal stroke, or vascular death compared to morning dosing (HR 0.95).
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