Population
166 subjects, comprising 20 normal young adult controls, 50 young patients with essential hypertension, and…
Design
Cross-sectional
Authors
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Supports age-stratified renin assessment in hypertension; hypothesis-generating for progression mechanisms and requires longitudinal validation before clinical use.
The renin-angiotensin system appears to be enhanced during the early developmental stages of essential hypertension in young patients and suppressed in older patients.
Nakamura et al. (1979) studied this question.
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