A mathematical technique successfully corrects errors in left ventricular volume calculations from implanted markers due to rotational changes.
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Reproducible LV volumes in animal casts support marker-based correction; leaves open human translation and clinical validation.
Endocardial markers implanted by catheter have been used to estimate the left ventricular volume by outlining the ventricle in orthogonal planes. However, if the position of the ventricle with respect to the biplane radiographic system changes, the projected outlines formed by the markers will narrow and the calculated volume will decrease. Therefore, a mathematical technique to correct this error was developed. It was tested by extensively rotating silicone casts of the left ventricle to which markers were glued. Except for one position at which the volume deviated by 4.5 ml, all the calculated volumes of the casts were reproducible to within 2 ml.
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Davis et al. (1982) studied this question.
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