Key result
Atrial fibrillation in patients with hypertension and preserved systolic function was significantly associated with alcohol intake ≥7 drinks/week (OR 4.12) and physical activity <150 min/week (OR 3.18).
Why the study?
Factors associated with atrial fibrillation in patients with hypertension and preserved left ventricle systolic function needed to be defined.
Cross-Sectional (n=273)
No
Odds Ratio: 4.12 (95% CI 1.04–16.35)
p-value: p=0.044
In urban patients with hypertension and preserved LVEF, modifiable lifestyle factors including alcohol intake, low physical activity, and obesity measures are significantly associated with the presence of atrial fibrillation.
Supports lifestyle counseling in hypertensive patients; hypothesis-generating for AF prevention and requires prospective validation.
The objective of our study was to define factors associated with atrial fibrillation (AF) in patients with hypertension (HTN) and preserved left ventricle systolic function. MATERIAL AND METHODS: Overall, 273 consecutive patients with HTN residing in urban area were included in the study. Patients were divided into 2 groups: the first - 60 patients with paroxysmal and persistent AF (33% men, age 62, 28 (10,02), the second - 213 patients without AF (33% men, age 59,37 (8,27). RESULTS: Stepwise logistic regression analysis demonstrated AF presence was associated with alcohol intake ≥ 7 drinks per week (OR 4,12; 95%CI: 1,04-16,35), low physical activity (OR 3,18; 95% CI: 1,32-7,68), higher hip circumference (OR 1,19; 95% CI: 1,08-1,31) and history of HTN (OR 1,10; 95% CI: 1,04-1,17). BMI was not associated with presence of AF (OR 0,75; 95% CI: 0,61-0,91). CONCLUSION: Thus in our urban population with hypertension, AF is associated with alcohol intake ≥ 7 drinks per week, low physical activity, increased hip circumference and history of hypertension.AF prevention should include modification of lifestyle.
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Tlegenova et al. (2019) conducted a cross-sectional in Hypertension with preserved left ventricle systolic function (n=273). Alcohol intake ≥7 drinks per week vs. Alcohol intake <7 drinks per week or none was evaluated on Presence of atrial fibrillation (OR 4.12, 95% CI 1.04-16.35, p=0.044). Atrial fibrillation in patients with hypertension and preserved systolic function was significantly associated with alcohol intake ≥7 drinks/week (OR 4.12) and physical activity <150 min/week (OR 3.18).
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