Why the study?
Does physiologic epinephrine infusion alter serum inorganic phosphorus and mineral metabolism hormones in healthy men?
Population
6 healthy male volunteers, 24-33 years of age, 66-92 kg
Comparison
Epinephrine infused intravenously at nominal… vs Baseline values and 30-min saline infusions
Design
Other, random sequences, unknown to the subjects
Follow-up
60 minutes per infusion
Authors
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May contribute to hypophosphatemia in catecholamine surges; hypothesis-generating for phosphate regulation in acute illness.
Does physiologic epinephrine infusion alter serum inorganic phosphorus and mineral metabolism hormones in healthy men?
Epinephrine in physiologic concentrations acts as a hypophosphatemic hormone in humans, likely by shifting phosphate intracellularly, without altering parathyroid hormone or calcitonin secretion.
Body et al. (1983) studied this question.
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