Population
Syrian Golden hamsters
Comparison
90-min infusion of 20% intralipid and heparin or… vs Saline control infusion
Design
Preclinical
Follow-up
90-min infusion after 5 weeks of diet/treatment
Authors
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Acute FFA elevation may stimulate intestinal lipoprotein production only in insulin-sensitive states; hypothesis-generating for human postprandial dyslipidemia mechanisms.
Acute elevation of plasma free fatty acids stimulates intestinal lipoprotein production in insulin-sensitive but not insulin-resistant states, where basal production is already elevated.
Lewis et al. (2004) studied this question.
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