Why the study?
Non-dipping blood pressure increases cardiovascular risk and correlates with inflammation, prompting investigation into the relationship between inflammation-based indexes and nocturnal BP patterns in normotensive individuals.
Are systemic inflammation indexes associated with a non-dipper nocturnal blood pressure pattern in normotensive individuals?
Are systemic inflammation indexes associated with a non-dipper nocturnal blood pressure pattern in normotensive individuals?
In normotensive individuals, a higher systemic immune-inflammation index (SII) is associated with a non-dipper nocturnal blood pressure pattern, suggesting a role for subclinical inflammation in altered circadian blood pressure rhythms.
SII may aid nocturnal BP risk stratification in normotensives; leaves open causal role and screening utility pending prospective validation.
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Günay et al. (2021) studied this question.
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