Why the study?
Does nocturnal blood pressure non-dipping associate with increased procoagulant and proinflammatory activity in unmedicated normotensive and hypertensive subjects?
Population
76 unmedicated normotensive and hypertensive subjects
Comparison
Non-dipping nocturnal blood pressure vs Dipping nocturnal blood pressure
Design
Cross-sectional
Authors
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Non-dipping BP was associated with higher D-dimer and vWF; hypothesis-generating for prothrombotic mechanism, should not yet change practice.
Does nocturnal blood pressure non-dipping associate with increased procoagulant and proinflammatory activity in unmedicated normotensive and hypertensive subjects?
Nocturnal blood pressure non-dipping is associated with elevated levels of procoagulant and endothelial dysfunction markers, providing a potential mechanism for the increased cardiovascular risk observed in these patients.
Jain et al. (2004) studied this question.
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