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November 15, 2012European Heart Journal - Cardiovascular ImagingOpen Access

Alterations of left ventricular myocardial strain in obese children

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Why the study?

Does childhood obesity alter left ventricular myocardial strain compared to healthy controls?

Population

64 children, comprising 32 consecutive obese patients (age: 12.8 years; 15 males; BMI Z-score: 5.8…

Design

Case-control

Authors

FLFabien LabombardaNormandie UniversitéEZE. ZanglADA. DuguéCentre François Baclesse

Discussion

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Implication

Childhood obesity was associated with reduced LV strain; hypothesis-generating for future risk and requires prospective validation.

Structured PICO

Does childhood obesity alter left ventricular myocardial strain compared to healthy controls?

P
Population
64 children, comprising 32 consecutive obese patients (age: 12.8 (8-17) years; 15 males; BMI Z-score: 5.8 [2.05-8.6]) and 32 age- and sex-matched controls.
C
Comparator
Age- and sex-matched controls
O
Outcome
Left ventricular myocardial strain (longitudinal, circumferential, and radial) measured by 2D speckle echocardiographysurrogate

Childhood obesity is associated with early subclinical alterations in left ventricular longitudinal and circumferential strain, which correlate with insulin resistance and reduced exercise capacity.

Cite This Study

Labombarda et al. (2012) studied this question.

synapsesocial.com/papers/6a736e706cf7a6ca1f6c3532https://doi.org/10.1093/ehjci/jes238

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Impact of Obesity on Left Ventricular Mass and Geometry1991 · 426 citations
  2. 2The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study1991 · 527 citations
  3. 3Standardization of M-mode echocardiographic left ventricular anatomic measurements1984 · 748 citations
  4. 4Prevalence of Overweight and Obesity Among US Children, Adolescents, and Adults, 1999-20022004 · 4,484 citations
  5. 5The effects of hyperinsulinaemia on myocardial mass, blood pressure regulation and central haemodynamics in rats1996 · 71 citations