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June 2, 2021MedicinaOpen Access

Atrial and Ventricular Structural and Functional Alterations in Obese Children

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Why the study?

Childhood obesity has reached epidemic levels, and this study aimed to determine early changes in cardiac structure and function in obese children compared to nonobese peers using echocardiography.

Does obesity alter atrial and ventricular structure and function in children?

Population

35 obese and 37 age-matched nonobese children

Comparison

Obese children vs nonobese peers

Design

Comparative cross-sectional study

Authors

RŠRima ŠileikienėKAKarolina AdamonytėAZAristida Ziutelienė

Discussion

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Overview

Obesity-linked subclinical cardiac changes detectable by speckle-tracking echo in children; hypothesis-generating for screening and outcome trials.

Structured PICO

Does obesity alter atrial and ventricular structure and function in children?

P
Population
72 children, comprising 35 obese children (aged 13.51 ± 2.15 years; 20 boys; BMI z-score of 0.88 ± 0.63) and 37 age-matched nonobese children.
C
Comparator
37 age-matched nonobese children
O
Outcome
Early changes in cardiac structure and function assessed by 2D, pulsed wave tissue Doppler, and 2D speckle tracking echocardiographysurrogate

Obese children exhibit subclinical myocardial dysfunction, including reduced atrial and ventricular strain, detectable by 2D speckle tracking echocardiography despite appearing healthy.

Cite This Study

Šileikienė et al. (2021) studied this question.

synapsesocial.com/papers/6a8692ec05076cf37f2d7947https://doi.org/10.3390/medicina57060562
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Alterations of left ventricular myocardial strain in obese children2012 · 43 citations
  2. 2Obesity, Behavioral Lifestyle Factors, and Risk of Acute Coronary Events2008 · 153 citations
  3. 3Two‐ and Three‐Dimensional Speckle Tracking Echocardiography: Clinical Applications and Future Directions2013 · 217 citations
  4. 4Fatty infiltration: Another restrictive cardiomyopathic pattern1991 · 21 citations
  5. 52016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents2016 · 1,402 citations