Why the study?
Does tumor resection normalize IL-6 levels in a child with right atrial myxoma presenting with rheumatic-like symptoms?
Does tumor resection normalize IL-6 levels in a child with right atrial myxoma presenting with rheumatic-like symptoms?
IL-6 should be considered a marker for cardiac myxoma, as its overproduction and systemic passage can cause immunological features mimicking rheumatic disease.
IL-6 may mark cardiac myxoma mimicking rheumatic disease in children; single case leaves open diagnostic utility and production site.
A 6‐y‐old girl with right atrial myxoma presented with remittent fever attacks, general arthralgia and laboratory investigations mimicking rheumatic or autoimmune disease. Interleukin‐6 (IL‐6) serum concentration was markedly elevated before and normal after tumour resection, whereas myxoma cells stained negatively for IL‐6. IL‐6 should be considered a myxoma marker: overproduction by myxoma cells and consecutive systemic passage are assumed to cause immunological features. □ Cardiac myxoma, childhood, interleukin‐6, rheumatic disease
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Hövels‐Gürich et al. (1999) studied this question.
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