Why the study?
Do short-acting nifedipine and diltiazem reduce cardiac events in patients with healed myocardial infarction?
Population
1115 patients with healed myocardial infarction
Comparison
Short-acting nifedipine 30 mg/d or short-acting… vs No calcium antagonist (n=595)
Design
Other, open-label
Authors
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Short-acting nifedipine or diltiazem offer no cardiac event reduction after healed MI; leaves open potential harm and warrants randomized trials.
Do short-acting nifedipine and diltiazem reduce cardiac events in patients with healed myocardial infarction?
Short-acting nifedipine and diltiazem do not reduce cardiac events in patients with healed myocardial infarction and showed a non-significant trend toward harm.
Ishikawa et al. (1997) studied this question.
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