Environmental surveillance in Finland detected 21 highly divergent, neurovirulent vaccine-derived polioviruses in sewage, highlighting the importance of monitoring for potential re-emergence.
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Persistent VDPV detection in sewage signals ongoing circulation risk; leaves open optimal surveillance frequency and vaccination thresholds.
In Finland, surveillance of potential re-emergence of poliovirus transmission is mainly based on environmental surveillance, i.e. search for infectious poliovirus in sewage samples. Since December 2008, 21 genetically highly divergent, neurovirulent vaccine-derived polioviruses (VDPV) have been isolated from sewage in Tampere, Finland. While the source of the VDPV is unknown, characteristics of the viruses resemble those of strains isolated from immunodeficient, persistently infected persons. No cases of suspected poliomyelitis have been reported in Finland since 1985.
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Roivainen et al. (2010) studied this question.
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