Why the study?
Does surrounding tissue affect the passive mechanics (wall strain and stress) of the vessel wall in swine?
Does surrounding tissue affect the passive mechanics (wall strain and stress) of the vessel wall in swine?
Surrounding tissues take up a considerable portion of intravascular pressure, significantly reducing vessel wall strain and stress, which must be considered when interpreting in vitro and in vivo mechanical properties of vessels.
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Perivascular tethering must be considered in vessel mechanics analyses; leaves open translation to human arterial behavior in vivo.
Liu et al. (2007) studied this question.
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