Why the study?
Weighted echocardiographic ratio indices are assumed to be least affected by body weight and size, but the effects of varying age, breed, and body weight required evaluation.
Weighted M-mode echocardiographic ratio indices are not significantly affected by breed, age, or body weight, suggesting they can be used for direct comparison in canine cardiac disease diagnosis across a wide range of body weights.
May refine LV reference ranges in dogs; leaves open human validation.
The study was conducted at TVCC-RVP IVRI, Izatnagar, Bareilly on 34 dogs of two different breeds, i.e.Spitz and Labrador Retriever.Seventeen healthy dogs of each breed were included and randomly divided into three groups of varying ages containing at least 5 animals in each group.M mode echocardiographic parameters were recorded for each animal for left ventricular cardiac measurements.The raw M mode measurements were divided by weight based aortic root dimension to obtain weighted echocardiographic ratio indices which are assumed to be least affected by body weight and size, and can be used for direct comparison between patient groups.Ratio indices were statistically analyzed to determine the effect of varying age and breed.Weighted left ventricular dimensions were correlated with body weight through Pearson's correlation coefficient to determine the effect of varying body weight over weighted ratio indices.The results signify a non-significant effect of breed, age, and body weight on derived ratio indices and thus can be suggested to be used for direct comparison for cardiac disease diagnosis in dogs despite of wide range of body weight.
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Hoque et al. (2023) studied this question.
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