Population
mSlo Ca(2+)-activated K(+) channels
Design
Preclinical
Authors
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Advances BK channel gating models in animals; leaves open translation to human cardiovascular therapies.
The study elucidates the allosteric voltage-gating mechanism of mSlo Ca(2+)-activated K(+) channels, demonstrating that gating currents exhibit multiple components associated with various state transitions.
Horrigan et al. (1999) studied this question.
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