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December 16, 2017Translational Sports Medicine

Effect of high-intensity exercise training on functional sympatholysis in young and older habitually active men

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Why the study?

Does 8 weeks of high-intensity exercise training improve functional sympatholysis in young and older habitually active men?

Population

30 habitually active, healthy male subjects (15 young, 25 ± 1 years; 15 older, 72 ± 1 years)

Comparison

8 weeks of high-intensity exercise training vs Baseline (before exercise training)

Design

Cohort

Follow-up

8 weeks

Authors

PPPeter PiilTJTue S. JørgensenJEJon Egelund

Discussion

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Member takes

Overview

High-intensity training may enhance functional sympatholysis across ages; leaves open effects in sedentary or diseased populations.

Structured PICO

Does 8 weeks of high-intensity exercise training improve functional sympatholysis in young and older habitually active men?

P
Population
30 habitually active, healthy male subjects (15 young, 25 ± 1 years; 15 older, 72 ± 1 years)
I
Intervention
8 weeks of high-intensity exercise training
C
Comparator
Baseline (before exercise training)
O
Outcome
α-adrenergic responsiveness at rest and functional sympatholysis during knee-extensor exercise (assessed via leg hemodynamics and venous plasma norepinephrine without and with tyramine infusion)surrogate

High-intensity exercise training improves functional sympatholysis in young but not older habitually active men, suggesting that improving sympatholytic capacity by training may be a slower process in aged individuals.

Cite This Study

Piil et al. (2017) studied this question.

synapsesocial.com/papers/6a73952799c817e23aa73173https://doi.org/10.1002/tsm2.1
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