Why the study?
Does 8 weeks of aerobic exercise training improve functional sympatholysis and postjunctional α-adrenergic responsiveness in hypertensive and normotensive individuals?
Population
16 untrained individuals, comprising 8 with essential hypertension and 8 normotensive individuals.
Comparison
8 weeks of aerobic exercise training. vs Pre-training baseline and normotensive controls.
Design
Cohort
Follow-up
8 weeks
Key result
Eight weeks of aerobic exercise training improved functional sympatholysis and reduced postjunctional α-adrenergic responsiveness in both normotensive and hypertensive individuals (P<0.05).
Authors
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Supports mechanistic role of exercise in vascular control; hypothesis-generating for BP benefits in hypertension.
Does 8 weeks of aerobic exercise training improve functional sympatholysis and postjunctional α-adrenergic responsiveness in hypertensive and normotensive individuals?
p-value: p=<0.05
Aerobic exercise training improves functional sympatholysis and reduces postjunctional α-adrenergic responsiveness in both hypertensive and normotensive individuals, providing a mechanistic basis for how exercise improves tissue perfusion and lowers blood pressure.
Mortensen et al. (2014) studied Essential hypertension (n=16). Aerobic exercise training vs. Pre-training state and normotensive individuals was evaluated on Functional sympatholysis and postjunctional α-adrenergic responsiveness (p=<0.05). Eight weeks of aerobic exercise training improved functional sympatholysis and reduced postjunctional α-adrenergic responsiveness in both normotensive and hypertensive individuals (P<0.05).
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