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August 29, 2023Journal of Clinical MedicineOpen Access

Prognostic Impact of Percutaneous Coronary Intervention in Older Patients Hospitalized with Acute Myocardial Infarction: Real-World Findings from the Lombardy Health Database

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Why the study?

Older patients are less likely to receive PCI for acute myocardial infarction compared with younger patients, prompting investigation of its prognostic impact in this population.

Does percutaneous coronary intervention reduce in-hospital and 1-year mortality in patients aged ≥75 years hospitalized with acute myocardial infarction?

Population

116,063 patients aged ≥75 years hospitalized with AMI in Lombardy, Italy

Comparison

PCI vs no PCI during index hospitalization

Design

Retrospective administrative database study

Follow-up

1 year

Authors

GMGiancarlo MarenziNCNicola CosentinoMRMarta Resta

Discussion

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Overview

PCI was associated with lower mortality in elderly AMI patients; leaves open whether routine use improves outcomes pending RCTs.

Structured PICO

Does percutaneous coronary intervention reduce in-hospital and 1-year mortality in patients aged ≥75 years hospitalized with acute myocardial infarction?

P
Population
116,063 patients aged ≥75 years hospitalized with a primary diagnosis of acute myocardial infarction (either STEMI or NSTEMI), mean age 83, 48% male, from the Lombardy Health Database (Italy).
I
Intervention
Percutaneous coronary intervention (PCI) during the index hospitalization
C
Comparator
No percutaneous coronary intervention (PCI) during the index hospitalization
O
Outcome
In-hospital mortalityhard clinical

In a large real-world cohort of patients aged ≥75 years with acute myocardial infarction, percutaneous coronary intervention was associated with significantly lower in-hospital and 1-year mortality.

Cite This Study

Marenzi et al. (2023) studied this question.

synapsesocial.com/papers/6a73a217ef8a0d4f3a4c9d36https://doi.org/10.3390/jcm12175629
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Percutaneous coronary intervention in nonagenarians with acute myocardial infarction: a 15-year population-based study2026 · 1 citations
  2. 2Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital2019 · 5 citations
  3. 3Long-Term Clinical Outcomes after Primary Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction Older than 75 Years2005 · 13 citations
  4. 4Improved short and long term survival associated with percutaneous coronary intervention in the elderly patients with acute coronary syndrome2018 · 21 citations
  5. 5Primary percutaneous coronary intervention for acute myocardial infarction in the elderly aged ≥75 years2011 · 29 citations