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July 1, 2019MedicineOpen Access

Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital

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Key result

PCI linked to ~68% lower in-hospital mortality in elderly patients with AMI.

  • OR 0.323
  • 95% CI 0.147-0.710
  • P=.005
  • n=387

Why the study?

The status of percutaneous coronary intervention (PCI) and the reasons for not receiving PCI in elderly patients with acute myocardial infarction (AMI) needed investigation.

Does percutaneous coronary intervention reduce in-hospital mortality in elderly patients (≥80 years) with acute myocardial infarction?

Population

387 consecutive hospitalized AMI patients aged ≥80 years

Comparison

PCI treatment vs no PCI treatment

Design

Cohort study

Authors

LCLi‐Wei ChenLHLing HanJLJing-guang Luo

Discussion

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Overview

Supports selective PCI use in elderly AMI patients; leaves open causality and generalizability pending randomized trials.

Study Design

Type

Cohort (n=387)

Structured PICO

Does percutaneous coronary intervention reduce in-hospital mortality in elderly patients (≥80 years) with acute myocardial infarction?

P
Population
387 consecutive hospitalized AMI patients aged ≥80 years, recruited from 2005 to 2014 to evaluate in-hospital mortality.
E
Exposure
Percutaneous coronary intervention (PCI)
C
Comparator
No PCI treatment (conservative management)
O
Outcome
In-hospital mortalityhard clinical

Main Result

Odds Ratio: 0.323 (95% CI 0.147–0.71)

p-value: p=.005

PCI is associated with significantly reduced in-hospital mortality in AMI patients aged ≥80 years, though utilization remains low due to comorbidities and delayed presentation.

Cite This Study

Chen et al. (2019) conducted a cohort in Acute myocardial infarction (AMI) (n=387). Percutaneous coronary intervention (PCI) vs. Not receiving PCI was evaluated on In-hospital mortality (OR 0.323, 95% CI 0.147-0.710, p=.005). Percutaneous coronary intervention was an independent protective factor for in-hospital mortality in elderly patients with acute myocardial infarction (OR 0.323; 95% CI 0.147-0.710; P=0.005).

synapsesocial.com/papers/6aaa5f08bdb30b5c2feb8a92https://doi.org/10.1097/md.0000000000016544
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Percutaneous coronary intervention in nonagenarians with acute myocardial infarction: a 15-year population-based study2026 · 1 citations
  2. 2Prognostic Impact of Percutaneous Coronary Intervention in Older Patients Hospitalized with Acute Myocardial Infarction: Real-World Findings from the Lombardy Health Database2023 · 3 citations
  3. 3Primary percutaneous coronary intervention for acute myocardial infarction in the elderly aged ≥75 years2011 · 29 citations
  4. 4Primary Percutaneous Coronary Intervention in Elderly Patients With Acute Myocardial Infarction ― An Analysis From a Japanese Nationwide Claim-Based Database ―2019 · 29 citations
  5. 5Assessment of Primary Percutaneous Coronary Intervention Outcomes in Elderly and Very Elderly Patients2022 · 1 citations