Why the study?
Does 4D-flow MRI identify hemodynamic differences in patients with venous pulsatile tinnitus compared to healthy controls?
Does 4D-flow MRI identify hemodynamic differences in patients with venous pulsatile tinnitus compared to healthy controls?
4D-flow MRI can accurately identify hemodynamic differences such as vortex/turbulence and drainage dominance in patients with venous pulsatile tinnitus, serving as a potential noninvasive biomarker.
4D-flow MRI vortex detection may aid venous PT evaluation; hypothesis-generating and requires larger validation before clinical adoption.
OBJECTIVE: To use 4D-flow MRI to characterize hemodynamics of transverse and sigmoid sinus in venous pulsatile tinnitus (PT) patients and to investigate their differences vs healthy controls. METHODS: ), and pulsatility index (PI) between PT and control group. RESULTS: , and slightly higher PI. For the assessment of flow pattern, inter-reader reproducibility was excellent (κ = 1.00). Vortex or turbulence was observed in PT patients with good sensitivity (86.4%) and specificity (90.9%). Drainage dominance was more frequently observed in patients (15/21, 71.4%) than healthy controls (4/11, 36.4%). CONCLUSIONS: Significant hemodynamic differences were found between venous PT patients and healthy controls with 4D-flow MRI. Hemodynamic conditions could serve as noninvasive biomarkers for diagnosis and treatment evaluation of venous PT. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that 4D-flow MRI accurately identifies patients with venous PT.
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Li et al. (2018) studied this question.
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