Why the study?
Does ziprasidone increase the risk of sudden cardiac death despite prolonging the ECG QT interval?
Population
Patients treated with ziprasidone for schizophrenia and bipolar disorder
Comparison
Ziprasidone vs Other second-generation antipsychotics and…
Design
Review
Authors
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Supports ziprasidone use despite QT prolongation; leaves open need for prospective cardiac outcome trials.
Does ziprasidone increase the risk of sudden cardiac death despite prolonging the ECG QT interval?
Ziprasidone prolongs the QT interval but does not appear to increase the risk of sudden cardiac death, while offering a favorable metabolic profile.
Leslie Citrome (2011) studied this question.
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