Why the study?
Does a high-fat meal induce endothelial dysfunction and oxidative stress in healthy subjects?
Population
16 healthy subjects (mean age, 30 +/- 5 years) without major coronary risk factors
Comparison
Standard high-fat meal vs Baseline (before meal)
Design
Cohort
Follow-up
6 hours
Authors
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May acutely impair endothelial function via oxidative stress; leaves open long-term CV risk from habitual high-fat intake.
Does a high-fat meal induce endothelial dysfunction and oxidative stress in healthy subjects?
A high-fat meal acutely induces endothelial dysfunction associated with increased oxidative stress in healthy subjects.
Tsai et al. (2004) studied this question.
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