Population
Isolated perfused papillary muscle of rat heart
Comparison
Perfusion with Tyrode's solution via the septal… vs Non-perfused muscle
Design
Preclinical
Authors
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Enables reliable IMP measurements in isolated rat muscle; leaves open translation to in vivo edema or mechanics pending further validation.
Reliable intramyocardial pressure measurements can be made in the isolated rat papillary muscle, demonstrating that increased interstitial filling increases its pressure.
Heslinga et al. (1996) studied this question.
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